Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.

PLoS One · 2017 · PMC5600405 · PMID 28915272

Europe PMC DOI

hedged sentences

0.0400

closest p · 0.8× alpha

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boldest claim

The sentences

a clear trendp = 0.04actually significant

In both CTR and DM1 muscle cells there was a clear trend towards an increased activation of the protein, however this activation was lower in DM1 (CTR vs DM1 p = 0.04; 15 minutes: CTR vs DM1 p = 0.04).

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did not reach statistical significanceno p-value reported

However, the fold changes in protein expression between CTR and DM1 observed in TA were similar to that observed in BB where the differences did not reach statistical significance due to the interindividual variability.

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