nominally significantP -value<0.05
HBMR outputs results as Bayes factors (BFs), and we declared a nominally significant finding when BF exceeded a threshold of 2.45 (corresponding to a P -value<0.05), as previously suggested. 49 , 50 Annotations All SNPs showing statistically significant association or linkage (FDR P <0.05) in the discovery analyses were annotated to infer potential functional consequences.