Analysis of the CD69 expression on total NK, CD56 dim , and CD56 bri NK cells showed that CD69 expression level was slightly decreased with aging, but did not reach statistical significance (Figure 3E ).
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Changes of peripheral lymphocyte subsets and cytokine environment during aging and deteriorating gastrointestinal tract health status.
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Thus, NKT cells remained largely stable with aging, while the expression of CD69 and CD57 on NKT cells showed a trend of increase with aging.