Systemic and Terminal Ileum Mucosal Immunity Elicited by Oral Immunization With the Ty21a Typhoid Vaccine in Humans.

Cell Mol Gastroenterol Hepatol · 2017 · PMC5626924 · PMID 29022005

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hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

approached significanceP < .1so close (0.05 < p ≤ 0.1)

S Typhi–specific CD8 + -T EM were significantly increased in LPMC ( P < .05) for CD107a expression and TNF-α production and approached significance ( P < .1) for IL17A production compared with PBMC.

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approaching significanceno p-value reported

In addition, we noted significantly higher levels of CD107a in PBMC CD8 + -T EMRA and approaching significance in IFN-γ in PBMC CD8 + -T EM as compared with their LPMC counterparts in unvaccinated volunteers ( Table 1 ; blue highlights).

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