Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder.

Soc Cogn Affect Neurosci · 2017 · PMC5629818 · PMID 28575424

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0700

boldest claim

The sentences

showed a trendP = 0.067so close (0.05 < p ≤ 0.1)

The depressed group showed a trend towards greater activation across both trial types in the right habenula compared with the healthy controls ( t (35) = 1.89, P = 0.067, Cohen's d = 0.65), but the difference in left habenula activation was non-significant ( t (35) = 0.77, P = 0.45, Cohen's d = 0.26).

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marginally significantP = 0.07so close (0.05 < p ≤ 0.1)

For RT to choose high-probability stimuli, there was a marginally significant effect of trial type ( F (1,35)=3.53, P = 0.07, partial η 2 =0.09), with faster responses on reward trials relative to punishment trials.

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approached significanceno p-value reported

No other main effects or interactions approached significance (all ps > 0.10) ( Figure 2 ).

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