A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene.

This means that the effect of high RLE score on either BSI-DEP or BSI-ANX was in average 4 times higher in TT compared to CC genotype individuals. The rs3219151xRLE interaction effect was nominally significant on DEP (p = 0.029, FDR-q = 0.077) and showed a trend on SUIC (p = 0.093, FDR-q = 0.186) but none of them survived correction for multiple testing.

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However, a highly significant association was reported in interaction with RLE for cognitive impulsiveness as measured by increased reaction times in T carriers in the STOP task reflecting increased latency in the ability to inhibit an already initiated response.

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