When high BMI category was dissected into obese and overweight groups, only overweight patients demonstrated statistically significant longer median survival (19 months) than normal BMI patients ( P = 0.033), whereas the relatively better survival outcomes (16 months) in obese patients did not reach statistical significance ( P = 0.078) (Fig. 1 b).
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The impact of baseline body mass index on clinical outcomes in metastatic breast cancer: a prospective study.
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showed a trend toward improved PFS and OS in overweight patients when compared with normal weight and obese patients, and therefore suggested that being overweight should not be regarded as an adverse prognostic factor in patients with MBC [ 10 ].