A significant peak in the last time period was considered as indicator for an increasing trend in IC50 values and thus, a trend towards bNAb resistance.
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Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time.
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The sentences
Though we find the last time periods as part of a significant trend in the data for PG9, PG16 and PG128, the partial p-values indicate rather a plateau distribution than a clear trend towards resistance in the last time periods (see S6 Table ).