LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH.

Fluids Barriers CNS · 2017 · PMC5696777 · PMID 29157263

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0700

boldest claim

The sentences

near-significantp = 0.054so close (0.05 < p ≤ 0.1)

fold increase analysis) revealed near-significant reductions in cerebral albumin ( p = 0.054, Fig. 2 b) and haemoglobin content ( p = 0.06, Fig. 2 d) by RAP.

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a strong trendp = 0.07so close (0.05 < p ≤ 0.1)

A strong trend for improved grip strength was further demonstrated with RAP in vehicle-treated ( p = 0.07 by t-test, Fig. 3 c), but not in rt-PA-treated animals.

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