Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis.

Cytotherapy · 2018 · PMC5758344 · PMID 28917625

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

a strong trendP = 0.052so close (0.05 < p ≤ 0.1)

There was a strong trend for duration of progressive disease to increase with age (Pearson r = 0.364; P = 0.052).

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did not reach statistical significanceno p-value reported

Neuronal survival following trophic factor withdrawal was reduced when MSCcm was isolated from patients with MS (MS-MSCcm) but, without correction for age and passage number, this effect did not reach statistical significance.

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