Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease.

PLoS One · 2018 · PMC5783363 · PMID 29364909

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Spliced variant of fibronectin, extra domain A ( ED-A ), showed a trend towards higher mRNA expression in the mucosa of IFX failure patients compared to IFX naïve patients (p = 0.08).

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did not reach statistical significanceno p-value reported

Crohn’s disease patients who had received prior treatment with IFX had more collagen I deposition compared to patients who were never treated with IFX, although this difference just did not reach statistical significance ( Fig 2 ).

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