Non-coding RNA dysregulation in the amygdala region of schizophrenia patients contributes to the pathogenesis of the disease.

Transl Psychiatry · 2018 · PMC5804029 · PMID 29391398

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp value = 6.198e−19actually significant

MIR1307 also maps to a highly significant SCZ GWAS locus (rs11191419, p value = 6.198e−19) in the PGC2 meta-analysis 30 .

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a clear trendno p-value reported

As shown in Table 3 , AC005009.2 replicated with a significant p value, and MIR1307 showed a clear trend toward association, with the same direction of effect, in the DLPFC data (Table 3 ).

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did not reach statistical significanceno p-value reported

The two other lncRNAs, RP11-724N1.1 and RP11-677M14.2 , did not reach statistical significance in the DLFPC data, which may either be reflective of tissue specificity or simply due to the reduced coverage in the DLPFC data.

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