Long-term Treatment with Low-Dose Caffeine Worsens BPSD-Like Profile in 3xTg-AD Mice Model of Alzheimer's Disease and Affects Mice with Normal Aging.

Front Pharmacol · 2018 · PMC5818407 · PMID 29497377

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Corticosterone levels showed slight increases due to genotype [G, F (1,30) = 1.983; p = 0.169, n.s.] that did not reach statistical significance.

also in 111,027 other papers

a clear trendno p-value reported

However, neuropsychiatric symptoms (NPS) are quite prevalent among the patients since early stages of Alzheimer’s disease ( Reisberg et al., 1987 ) and show a clear trend toward increasing their frequency with the progress of the disease ( Piccininni et al., 2005 ).

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.