Although results did not reach statistical significance, we found that HetAT subjects with shorter telomeres were more prone to develop cancer at any site than the other groups ( P trend = 0.03).
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Telomere length, ATM mutation status and cancer risk in Ataxia-Telangiectasia families.
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Regarding the contribution of the seven selected SNPs and cancer risk, only rs6060627 in BCL2L1 showed suggestive association with overall cancer risk, with a significant trend when the analysis was focused on females ( P trend = 0.03) ( Table 5 ).