The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men.

Invest Ophthalmol Vis Sci · 2018 · PMC5886029 · PMID 29610859

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0700

boldest claim

The sentences

highly significantP = 0.0001actually significant

Results The association of V83I with POAG in AA was highly significant for men (odds ratio [OR] 6.5; 95% confidence interval [CI] 2.0–21.3, P = 0.0001), but not for women (OR 1.1; 95% CI, 0.62–2.00, P = 0.78).

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nominally significantP = 0.049actually significant

However the distribution of CCT across three bins was nominally significant ( P = 0.049), with the largest fraction of V83I patients having CCT greater than 540 μm.

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did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

IOP was lower in the L1c2 group despite their worse disease, although the difference did not reach statistical significance ( P = 0.07).

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