Use of dietary indices to control for diet in human gut microbiota studies.

The HFD-index was approaching significance with axis 2 (β = − 0.039, p = 0.055) and axis 8 (β = − 0.095, p < 0.0001) (Additional file 1 : Table S16).

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We observed that of the 167 HEI-associated OTUs, 71 were nominally significant in difference between “healthy diet” to “less healthy diet” pairs, and 17 were FDR-adjusted significant to q < 0.05 (Fig. 2 ).

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