In contrast, hyaluronidase plasma levels showed a trend toward higher levels in the HES 130/0.4 group at 8 and 24 h after CLP, which did not reach statistical significance (Additional file 1 : Figure S1).
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6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice.
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