Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo.

MAbs · 2018 · PMC5939987 · PMID 29553863

Europe PMC DOI

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did not reach statistical significanceno p-value reported

However, these differences did not reach statistical significance.

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showed a trendno p-value reported

The neutrophils showed a trend towards more lysis with monomeric IgA1 and IgA2 than with IgG, which had comparable efficacy to dimeric and secretory IgA.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.