12-year trends in cardiovascular risk factors (2002-2005 through 2011-2014) in patients with cardiovascular diseases: Tehran lipid and glucose study.

Unfortunately a significant trend was observed for smoking status from 11.05% in phase 2 to 16.83% in phase 4 (p = 0.042).

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Furthermore, marginally significant trend was observed for the prevalence of CKD (44.16% in phase 2 vs. 51.65% in phase 5, p value = 0.054).

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Despite a favorable trend for dyslipidemia, at the end of follow-up, about 97% of patients had levels of LDL-C ≥ 1.8102 mmol/L and over 50% did not report consumption of lipid lowering medication.

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Discussion During more than a decade long follow-up of a Middle Eastern population with prevalent CVD, an increasing trend was observed in the prevalence of general and central obesity, type 2 diabetes mellitus, CKD and physical inactivity.

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Unfortunately, our study revealed an unfavorable trend in the levels of physical inactivity, reaching over 50% in all patients.

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