Linalyl acetate prevents hypertension-related ischemic injury.

Although there was a modest trend toward increased ACh-induced vasorelaxation with linalyl acetate pretreatment at 25, 50, or 100 mg/kg or with 15 mg/kg ASA pretreatment, compared with the hypertension + OGD group, these differences did not reach statistical significance ( Fig 6B ).

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At doses of 50 mg/kg and 100 mg/kg, linalyl acetate injection also showed a trend toward decreased DBP, but the reductions were not significant ( Fig 2B ) Inhibitory effect of linalyl acetate on p47 phox expression in the hypertension-ischemia injury model Utilizing Western blot analysis, we investigated hypertensive ischemic injury-induced changes in p47 phox expression and corresponding inhibitory effects of linalyl acetate.

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