Vaccine antigens modulate the innate response of monocytes to Al(OH)3.

PLoS One · 2018 · PMC5973561 · PMID 29813132

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a clear trendno p-value reported

Although both proteins were not significantly regulated compared to the other stimulation condition a clear trend was observed.

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showed a trendno p-value reported

DTaP induces type I interferons and IFNγ, but downstream signaling is stronger in monocytes stimulated with plain Al(OH) 3 After 24 hours of stimulation, both Al(OH) 3 and DTaP-stimulated monocytes showed a trend towards increased gene expression of the type I interferon IFNβ .

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