Tanshinol stimulates bone formation and attenuates dexamethasone-induced inhibition of osteogenesis in larval zebrafish.

J Orthop Translat · 2016 · PMC5986998 · PMID 30035064

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showed a trendno p-value reported

As shown in Figure 6 , zebrafish larvae treated with Dex showed a trend toward reduction of the expression of osteoblast-specific genes, including runx2a, osteocalcin (OC), ALP, and osterix (sp7) , compared with the corresponding control.

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a significant trendno p-value reported

Meanwhile, the activities of SOD, glutathione peroxidase, and CAT showed a significant trend toward reduction in zebrafish larvae treated by Dex.

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