Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration.

PLoS One · 2018 · PMC6019671 · PMID 29944697

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did not reach statistical significanceno p-value reported

The percentage of monocytes expressing PD-L1 trended higher in MDR septic individuals (55.14± 4.3% vs 47.11± 2.75%, p = 0.124), this relationship did not reach statistical significance.

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a strong trendno p-value reported

There was a strong trend toward increased mortality in patients whose T cells failed to increase IFN-γ production in response to the three treatments.

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