The duration of hypothermia affects short-term neuroprotection in a mouse model of neonatal hypoxic ischaemic injury.

Exposure to 1.5h of hypothermia did not affect the levels of TUNEL+ cell death ( Fig 3B ), and showed a trend towards reduced microglial activation based on αMβ2 integrin immunoreactivity but did not reach statistical significance overall (Mixed Linear Model treating region as a repeated measure p = 0.332) or in any of the examined brain regions ( Fig 3C ).

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