However, the current density of L1670W was significantly reduced by about 50% in comparison with that recorded with WT channels (Figure 6A , inset), differently than in tsA-201 cells incubated at 30°C, in which L1670W current density showed a trend towards reduction that did not reach statistical significance (Figure 2 ).
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Gain of Function for the <i>SCN1A</i>/hNa<sub>v</sub>1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine.
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