Consanguinity and major genetic disorders in Saudi children: a community-based cross-sectional study.

Table 1 depicts the results of an analysis of consanguinity among all participants, indicating similar results to those for first-degree cousins, with a P value close to statistical significance for malformations ( P =.067) and a clearly significant association with CHD ( P =.003).

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There was a borderline significant association between first-cousin consanguinity and malformations ( P =.05).

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Nevertheless, the effect of consanguinity, in all participants, first-cousin and otherwise, was also determined and showed a trend in the level of significance of association similar to that of the first-cousin relationships.

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