Left lateralized cerebral glucose metabolism declines in amyloid-β positive persons with mild cognitive impairment.

Neuroimage Clin · 2018 · PMC6084012 · PMID 30101060

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0.6000

closest p · 12.0× alpha

0.6000

boldest claim

The sentences

did not reach statistical significancep > .6not close (p > 0.1)

Nevertheless, in MCI-AD subjects, these associations did not reach statistical significance (all p > .6 FWE c ) with the largest cluster located within subcortical structures (i.e. caudate nucleus).

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weakly significantno p-value reported

For Category Fluency (animals) significant deficits were found at baseline for dementia-AD and MCI-AD (dementia-AD>MCI-AD>CU) with weakly significant 24-month decline (dementia-AD/MCI-AD>CU). 3.2 24-month rCMRgl declines Compared to CU, MCI-AD patients showed rCMRgl declines predominantly located within the left lateral temporal cortex (pFWE c < 0.05) (see Fig. 2 and Table 2 ).

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