Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?

Ann Clin Transl Neurol · 2018 · PMC6093846 · PMID 30128317

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approached significanceno p-value reported

The genotypes rs6733839 in the BIN 1 gene and rs28834970 in the PTK 2B gene approached significance in the PENN cohort and were significantly associated with reduced AD risk in the NACC cohort.

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of marginal significanceno p-value reported

We additionally observed two genotypic associations of marginal significance in the PENN cohort also reflecting lower AD risk in PART patients.

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