Distinct metabolic profile according to the shape of the oral glucose tolerance test curve is related to whole glucose excursion: a cross-sectional study.

After adjustment, the differences in 30-min (30minPG), 1-h and 90-min (90minPG) plasma glucose concentration, glucose AUC, Gutt, insulinogenic and disposition indices, and HDL cholesterol levels remained statistically significant, and, while a trend for the monophasic group to have higher 2-h plasma glucose and serum insulin concentrations persisted, the differences did not reach statistical significance.

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The monophasic group showed a trend toward obesity when compared to the biphasic group, with higher BMI and waist circumference (in both males and females), though these differences did not achieve statistical significance.

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