As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.
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Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A.
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