A distinct class of antioxidant response elements is consistently activated in tumors with NRF2 mutations.

Redox Biol · 2018 · PMC6128101 · PMID 30195190

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closest p · 1.0× alpha

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boldest claim

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nominally significantp-value <0.05actually significant

HMOX1 induction is nominally significant in HNSC (Wilcoxon p-value <0.05), and is not significant in UCEC or BLCA.

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a clear trendno p-value reported

We observed a clear trend that the genes upregulated in multiple cancer types were more likely to be direct NRF2 targets ( Fig. 1 C).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.