Clinical trial protocol of the ASTER trial: a double-blind, randomized, placebo-controlled phase III trial evaluating the use of acetylsalicylic acid (ASA) for enhanced early detection of colorectal neoplasms.

BMC Cancer · 2018 · PMC6154882 · PMID 30249195

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

A recent observational study on acetylsalicylic acid use and iFOBT performance showed a trend towards an increase in sensitivity (from 51.2 to 66.7%) without loss of specificity in acetylsalicylic acid or NSAID users, but the difference did not reach statistical significance, likely due to a relatively low number of acetylsalicylic acid/NSAID users [ 20 ].

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