Melatonin in Assisted Reproductive Technology: A Pilot Double-Blind Randomized Placebo-Controlled Clinical Trial.

Front Endocrinol (Lausanne) · 2018 · PMC6157331 · PMID 30283403

Europe PMC DOI

hedged sentences

0.4000

closest p · 8.0× alpha

0.4000

boldest claim

The sentences

did not reach statistical significancep = 0.4not close (p > 0.1)

The clinical pregnancy rate for all the women who took melatonin (all three groups combined) was higher than those taking a placebo, but this did not reach statistical significance [21.7 vs. 15.0%, OR 1.57 (95% CI 0.59, 4.14), p = 0.4, absolute risk reduction (ARR) 6.7% (95% CI −6.6, 20.0%)].

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a suggestive trendno p-value reported

While this study showed no clear evidence for an improvement in pregnancy rates, a suggestive trend encourages us to consider a definitive study with livebirth productivity rate as the appropriate measure.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.