Differentiation and quantification of fibrosis, fat and fatty fibrosis in human left atrial myocardium using ex vivo MRI.

PLoS One · 2018 · PMC6175289 · PMID 30296279

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.1400

boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

Overall, the higher correlation coefficient was found between native T1 and interstitial fibrosis fraction from MRI ( Fig 3B ), however this did not reach statistical significance ( P = 0.07).

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a negative trendP = 0.14not close (p > 0.1)

Native mean T1 values presented a significant and positive correlation with interstitial histological fibrosis fraction (r = 0.71, P = 0.03) but not with total histological fibrosis (r = 0.28, P = 0.46) and a negative trend of correlation with fatty fibrosis (r = -0.53, P = 0.14) and fat histological fraction (r = -0.60, P = 0.09) ( Fig 3E and 3H ).

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highly significantno p-value reported

Indeed, highly significant correlations were found for the aforementioned tissue components when comparing MRI quantitative measurements to histology.

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