Comparison of methods for transcriptome imputation through application to two common complex diseases.

Eur J Hum Genet · 2018 · PMC6189136 · PMID 29976976

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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The sentences

just missed significancep =1.10 x10 -5actually significant

6 , 7 were significant in our results (Bonferroni corrected p <5.61x10 -6 ), while BSN just missed significance ( p =1.10 x10 -5 ).

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approached significanceno p-value reported

Although few significant associations were observed, genes approached significance on chromosomes 3 and 6 in all tissues.

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approaching significanceno p-value reported

Both PrediXcan and MetaXcan found significant associations on chromosomes 3 ( C3orf62 ), 5 ( SLC22A5 , IRGM ) and 17 ( PGS1 ), while FUSION found associations approaching significance on chromosomes 3 ( UBA7 in a similar position to C3orf62 ) and 5 ( SLC22A5 ).

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