Interactions Between <i>ABCB1</i> Genotype and Preoperative Statin Use Impact Clinical Outcomes Among Breast Cancer Patients.

Front Oncol · 2018 · PMC6194198 · PMID 30370250

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP = 0.060so close (0.05 < p ≤ 0.1)

TT genotype appeared inversely related to the risk of breast cancer events compared to any C-carriers but the results did not reach statistical significance and the bounds of the 95% CIs did not exclude the null (Log-Rank 1 d.f., P = 0.060, adjusted Hazard Ratio (HR adj ) 0.74; 95% CI 0.49, 1.12).

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nominally significantno p-value reported

In conclusion, there were nominally significant interactions between ABCB1 genotype and preoperative statin use on clinical outcomes, while preoperative statin use was not associated with outcomes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.