IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators.

Front Endocrinol (Lausanne) · 2018 · PMC6196226 · PMID 30374330

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Collagen 1A1 expression showed a trend toward an increase at 28 h (Figure 3B ), although the difference did not reach statistical significance, unlike the response to rBP5 treatment.

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an increasing trendno p-value reported

rBP5 treatment significantly increased expression of the ECM gene collagen 1A1 (Col) and showed an increasing trend in fibronectin (FN) (Figures 2A,B ).

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