HOMA-IR was significantly higher, and Matsuda ISI was significantly lower in higher categories of the AHI ( p for the trend < 0.01), but after adjusted for BMI, both indices no longer showed a significant trend, indicating that the association between AHI severity and insulin resistance was confounded by BMI.
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Associations between Sleep-Disordered Breathing and Metabolic Risk Factors beyond Obesity.
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The sentences
In participants without obesity, the prevalence of low HDL-cholesterolemia and hyperglycemia tended to be higher in higher categories of the AHI but the trend test did not reach statistical significance.