Antagonizing the corticotropin releasing hormone receptor 1 with antalarmin reduces the progression of endometriosis.

PLoS One · 2018 · PMC6235236 · PMID 30427841

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0880

boldest claim

The sentences

did not reach statistical significancep> 0.05actually significant

Corticosterone levels were slightly elevated in rats with endometriosis regardless of treatment, however this difference did not reach statistical significance (F (2,43) = 1.99, p> 0.05; Fig 7A ).

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a strong trendp = 0.088so close (0.05 < p ≤ 0.1)

Despite a lower locomotor activity, there was a strong trend for both groups of rats with endometriosis to spend less time in the open arms of the zero maze (F (2,47) = 2.54, p = 0.088; Fig 5D ) suggesting increase anxiety.

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