Sex- and Development-Dependent Responses of Rat Microglia to Pro- and Anti-inflammatory Stimulation.

Front Cell Neurosci · 2018 · PMC6262307 · PMID 30524242

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a clear trendno p-value reported

While there were no statistically significant sex differences, there was a clear trend toward a larger response of female cells to IL-4.

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did not reach statistical significanceno p-value reported

IL-4 also increased COX-2 protein, consistent with the increases in mRNA (8.4-fold in males, 11.3-fold in females), but protein changes did not reach statistical significance.

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