Preliminary Study of the Effect of Stereotactic Body Radiotherapy (SBRT) on the Immune System in Lung Cancer Patients Unfit for Surgery: Immunophenotyping Analysis.

Int J Mol Sci · 2018 · PMC6320787 · PMID 30544863

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

showed a trendp = 0.066so close (0.05 < p ≤ 0.1)

Changes of total lymphocytes during the study period after the administration of SBRT showed a trend towards statistical significance using Friedman one-way ANOVA ( p = 0.066).

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failed to reach statistical significanceno p-value reported

These changes failed to reach statistical significance, but included an increase of the immunoactive component of the immune system with elevation of CD56+highCD16+ NK-cells, and a decrease of immunosuppressive component with decreases of CD4+CD25+Foxp3+CD45RA− regulatory T cells and G-MDSC and Mo-MDSC.

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