Multimodal intervention improves fatigue and quality of life in subjects with progressive multiple sclerosis: a pilot study.

High responders also showed a strong trend toward longer average daily duration of meditation (median: 11.8 minutes vs 7.9 minutes, P =0.079) and higher average exercise–NMES adherence (median: 85.9% vs 73.3%, P =0.109) than low responders ( Figure 4C and D ).

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Friedman’s test showed no significant change in other Short Form-36 subscale scores; however, median scores of physical functioning, role physical, pain, and social functioning showed a trend toward increase (improvement) from baseline during the 12 months ( Figure S2 ).

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