In our study, we did not find a statistically significant elevation in serum IGF-1 levels in the GH-treated group; however, there was a clear trend toward elevation in the treated group and we believe this likely represents a type-II error.
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Growth Hormone Improves Nerve Regeneration, Muscle Re-innervation, and Functional Outcomes After Chronic Denervation Injury.
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While we did not observe statistically significant differences in these markers, we did note trends towards increased expression in GH-treated animals for all markers, approaching significance for erbB3 and p75 expression.