Regulatory T-cell Number in Peripheral Blood at 1 Year Posttransplant as Predictor of Long-term Kidney Graft Survival.

Those patients with Treg cell levels at 12 months which were >19.51 cells/mm 3 were considered “High Treg cell group,” whereas those with Treg cell <7.63 cells/mm 3 were included in “Low Treg cell group.” Patients in the high Treg cell group had better death-censored graft survival, although this did not reach statistical significance (Log-rank P = .146) (Figure 4 ).

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Indeed, those patients who received induction therapy almost doubled the number of Treg cells at 12 month posttransplantation, and a high number of circulating Treg cells 12-month posttransplantation showed a trend to protect from DCGL in multivariate analysis, although it did not reach statistical significance ( Table S5 ).

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