Outcome for triple negative breast cancer in a retrospective cohort with an emphasis on response to platinum-based neoadjuvant therapy.

However, a marginally significant improvement in BCSS was seen in patients receiving adjuvant therapy compared to NACT (log-rank test, p = 0.049).

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DFS was improved with platinum therapy but the association did not reach statistical significance on univariate (HR non-pCR = 0.34; 95% CI 0.75–1.50; p = 0.153) or multivariable analysis (Supplementary Table 4).

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There was a significant trend of association between increasing ypT category and adverse DFS ( χ 2 test for trend, 13.56; p = 0.002), MFS ( χ 2 test for trend, 12.90; p = 0.0003) and BCSS ( χ 2 test for trend, 11.14; p = 0.0008).

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