Association of Bilateral Salpingo-Oophorectomy Before Menopause Onset With Medial Temporal Lobe Neurodegeneration.

JAMA Neurol · 2019 · PMC6439881 · PMID 30326011

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failed to reach statistical significanceno p-value reported

Limitations Lower hippocampal volume and higher cortical β-amyloid accumulation observed in the BSO group compared with the control group may have failed to reach statistical significance because of the small sample size.

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did not reach statistical significanceno p-value reported

Smaller hippocampal volume on MRI and higher cortical PiB standard uptake value ratio on PiB-PET scan were observed in the BSO group compared with the control group, but these results did not reach statistical significance ( Figure 2 ).

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