approached significancep = 0.068
Other findings that were nominally significant, or approached significance, that were also in the expected direction were the PRS for essential hypertension (OR = 0.89, p = 0.068) and LDL (OR = 0.89, p = 0.077).
Other findings that were nominally significant, or approached significance, that were also in the expected direction were the PRS for essential hypertension (OR = 0.89, p = 0.068) and LDL (OR = 0.89, p = 0.077).
Analyses were also adjusted for APOE ε4 and APOC3 C homozygotes ( Tables S14 and S15 ; when adjusting for APOE ε4, three cardiovascular health PRS (HDL, TG and myocardial infarction (MI)) were marginally significant but would not survive multiple testing correction.
Two cardiovascular health PRS were nominally significant with longevity (HDL cholesterol, triglycerides), with higher PRS associated with EL, but these relationships did not survive correction for multiple testing.