Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler's Murine Encephalomyelitis.

Int J Mol Sci · 2019 · PMC6480673 · PMID 30959793

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0730

boldest claim

The sentences

a strong trendp = 0.051so close (0.05 < p ≤ 0.1)

TMEV-infected Mmp12 −/− mice showed transiently reduced astrogliosis in association with a strong trend ( p = 0.051) for a reduced density of activated/reactive microglia/macrophages compared with wild-type mice at 28 dpi.

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showed a trendp = 0.073so close (0.05 < p ≤ 0.1)

In parallel to the reduced density of activated/reactive microglia at 98 dpi, TMEV-infected Mmp12 −/− showed a trend ( p = 0.073) for a reduced density of M1 (CD16/32- and CD107b-positive) microglia, while no difference regarding the density of M2 (arginase I- and CD107b-positive) cells was observed.

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