near-significantP <0.1
showed a trendP <0.1
Significant differences are indicated in the figures as follows: * P <0.05; ** P <0.01; *** P <0.001; # P <0.05; ## P <0.01; ### P <0.001; † P <0.05. Near-significant differences that showed a trend (0.05< P <0.1) are also indicated in the Figures.