CM37 treatment resulted in elevated ROS production in OVCAR5 cancer cells, although the increase did not reach statistical significance ( p = 0.06) ( Figure 6 A,B).
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A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer.
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These emerging results point to growing interest exploring this pathway, which is clearly significant to the survival of drug-resistant cancer cells.